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Shup : The free multi-host screenshot, image, and file uploader for Windows

Shup is great for uploading all kinds of files, especially when combined with the included Windows shell extension. With it, you can upload with Shup by right-clicking on a file in Explorer! Not only can Shup upload all kinds of files, it can also upload to many different hosts, including:

Flickr
ImageShack
PhotoBucket
Stashbox
REAPER Resource Repositorium
Waffle Images
You can also create custom site profiles and upload to your own web server; we even provide a sample PHP script to get you started.

[From: Shup : The free multi-host screenshot, image, and file uploader for Windows]